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Cofactor manipulation can have major effects on metabolism

 

Publications Regarding Cofactors

 

1          Vadali, R.V., Bennett, G.N., and San, K.-Y. "Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli."  Metabolic Engineering, 6 (2004): 294-299.  [Full Text]

 

4          Vadali, R.V., Bennett, G.N., and San, K.-Y. "Cofactor engineering of intracellular CoA/Acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli."  Metabolic Eng., 6 (2004): 133-139.  [Full Text]

 

7          Berrios-Rivera, S.J., Sanchez, A.M., Bennett, G.N., and San, K.-Y. "Effect of different levels of NADH availability on metabolite distribution in Escherichia coli in minimal and complex media."  Appl. Microbiol. Biotechnol., 65 (2004): 426-432.  [Full Text]

 

34        Berrios-Rivera, S.J., San, K.-Y., and Bennett, G.N. "The effect of NAPRTase overexpression on the total levels of NAD, NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coli."  Metabolic Engineering, 4 (2002): 238-247.  [Abstract]

 

35        Berrios-Rivera, S.J., Bennett, G.N., and San, K.-Y. "The effect of manipulating NADH availability on the redistribution of metabolic fluxes in Escherchia coli chemostat cultures."  Metabolic Engineering, 4 (2002): 230-237. 

 

37        Berrios-Rivera, S.J., Bennett, G.N., and San, K.-Y. "Metabolic engineering of Escherichia coli: increase of NADH availability by overexposing an NAD(+)-dependent formate dehydrogenase."  Metabolic Engineering, 4 (2002): 217-229.  [Full Text]

 

38        San, K.-Y., Bennett, G.N., Berrios-Rivera, S.J., Vadali, R.V., Yang, Y.-T., Horton, E., Rudolph, F.B., Sariyar, B., and Blackwood, K. "Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli."  Metabolic Eng., 4 (2002): 182-192.  [Full Text]