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Myoglobin Notebook

A library of structural and functional data on Mb mutants to develop general heme protein engineering principles and for designing individual heme proteins for specific pharmacological and industrial uses.

Publications

Papers since 2004 (out of ~200 refereed publications)

Smagghe, B. J., Hoy, J. A., Percifield, R., Kundu, S., Hargrove, M. S., Sarath, G., Hilbert, J-L., Watts, R. A., Dennis, E. S., Peacock, W. J., Dewilde, S., Moens, L., Blouin, G. C., Olson, J. S., and Appleby, C. Correlations between Oxygen Affinity and Sequence Classifications of Plant Hemoglobins, Biopolymers, in press (2009). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19441024

Yu, X., Mollan, T. L., Butler, A., Gow, A. J., Olson, J. S., and Weiss M. J. "Analysis of Human α Globin Gene Mutations that Impair Binding to the Alpha Hemoglobin Stabilizing Protein (AHSP)," Blood 113, 5961-5969 (2009). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19349619

Asmundson, A. L., van der Walde, A., Lin, D. H, Olson, J. S., and Anthony-Cahill, S. J., Co-Expression of Human α- and Circularly Permuted β-Globins Yields a Hemoglobin with Normal R state but modified T state Properties, Biochemistry 48, 5456-5465 (2009). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19397368

Aranda, R, Cai, H., Worley, C. E., Levin, E. J., Li, R., Olson, J. S., Phillips, G. N. Jr., and Richards, M. P., Structural analysis of bovine, trout IV, and perch hemoglobin: Effects of the heme pocket environment on autooxidation and hemin loss rates, Proteins 75 217-230 (2009). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18831041

Salter, M. D., Nienhaus, K., Nienhaus, G. U., Dewilde, S., Moens, L., Pesece, A., Nardini, M., Bolognesi, M., and Olson, J. S. The Apolar Channel in Cerebratulus lacteus Hemoglobin is the Route for O2 Entry and Exit. J. Biol. Chem. 283, 35689-35702 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18840607

Maillett, D. H., Simplaceanu, V., Shen, T-J., Ho, N.T., Olson, J. S., and Ho, C. Interfacial and distal pocket mutations exhibit additive effects on the structure and function of hemoglobin. Biochemistry 47, 10551-10563 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18788751

Hussain, F., Olson, J. S., and Wittung-Stafshede, P. Conserved residues modulate protein stability and copper release in human copper chaperone Atox1. Proc Natl. Acad. Sci., USA, 105, 11158-63 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18685091

Villarreal, D.M., Phillips, C. L., Kelley, A. M., Villarreal, S., Villaloboz, A., Hernandez, P., Olson, J. S., and Hendersen, D. P. Enhancing Recombinant Hemoglobin Production in Escherichia coli BL21(DE3) containing the Plesiomonas Shigelloides Heme Transport System. J. Appl. Enviro. Micro. 74, 5854-6 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18676700

Olson, J. S. From O2 Diffusion Into Red Blood Cells To Ligand Pathways In Globins. Chapter 14 (pp. 161-182) in DIOXYGEN BINDING AND SENSING PROTEINS, A Tribute to Beatrice and Jonathan Wittenberg (Eds. M. Bolognesi, G. di Prisco, C. Verde), Springer-Verlag Italia Srl, Milano, Italy, July 2008.

Graves, P.E., Henderson, D. P., Horstman, M. J., Solomon, B. J., and Olson, J. S. Enhancing Stability and Expression of Recombinant Hemoglobin in E. coli: Progress in the Development of a Recombinant HBOC Source.  Biochem. Biophys. Acta. Proteins and Proteomics, 1784, 1471-1479 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18489914

Zhu, H., Xie, G., Liu, M., Olson, J. S., Fabian, M., Dooley, D. M., and Lei, B. Pathway for Heme Uptake from Human Methemoglobin by the Iron-Regulated Surface Determinants (Isd) System of Staphylococcus aureus. J. Biol. Chem. 283, 18450-60 (2008). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18467329

Aranda, R., Worley, C. E., Liu, M., Bitto, E., Cates, M. S., Olson, J. S., Lei, B., and Phillips, G. N. Jr.  Bis-methionyl coordination and heme stacking in the crystal structure of the heme-binding domain of the streptococcal cell surface protein Shp J. Mol. Biol. 374, 374-83 (2007). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17920629

Ran, Y., Zhu, H.,  Liu, M., Fabian, M., Olson, J. S., Aranda, R. IV., Phillips, G. N., Jr., Dooley, D. M., and Lei, B.  Bis-Methionine Coordination in Shp Facilitates Rapid Heme Transfer to HtsA of the HtsABC Transporter in a Plug-in Mechanism. J. Biol. Chem. 282, 31380-8 (2007). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17699155

Olson, J. S., and Ghosh, A, "Mammalian Myoglobin as a Model for Understanding Ligand Affinities and Discrimination in Heme Proteins," Chapter 1, The Smallest Biomolecules: Perspectives on Heme-Diatomic Interactions (Ed. Abhik Ghosh) Elsevier, London, in press (2007).

Mocny, J. C., Olson, J. S., and Connell, T. D. Passively released heme from hemoglobin and myoglobin is a potential source of nutrient iron for  Bordetella bronchisepticaInfection & Immunity, 75, 4857-66 (2007). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17664260

Olson, J. S., Soman, J., and Phillips, G. N. Jr.  Ligand Pathways in Myoglobin: A Review of Trp Cavity Mutations, IUBMB  Life 59, 552-562 (2007). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17701550

Deng, P., Nienhaus K., Palladino, P., Olson J. S., Blouin. G., Moens, L., Dewilde, S., Geuens, E., and Nienhaus, G. U. Transient Ligand Docking Sites in Cerebratulus lacteus Mini-Hemoglobin, Gene 398, 208-223 (2007) http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17531406

Zhou, S., Olson, J. S., Fabian, M., Weiss, M. J., and Gow, A. J. Biochemical fates of alpha hemoglobin bound to alpha hemoglobin stabilizing protein (AHSP) J. Biol. Chem. 281, 32611-8 (2006).  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16901899

Nygaard, T. K., Blouin, G. C., Liu, M., Fukumura, M., Olson, J. S., Fabian, M., Dooley, D. M., and Lei, B., The Mechanism of Heme Transfer from the Streptococcal Cell Surface Protein Shp to HtsA of the HtsABC Transporter J. Biol. Chem., 281, 20761-71 (2006). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16717094

Gardner, P.A., Gardner, A.M., Brashear, W.T., Suzuki, T., Hvitved, A.N., Setchell, K.D.R., and Olson, J.S., Hemoglobins Deoxygenate NO with High Fidelity, Journal of Inorganic Biochemistry, 100, 542-550 (2006). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16439024

Goldbeck, R.A., Bhaskaran, S., Ortega, C., Mendoza, J., Olson, J. Soman, J., Kliger, D.S., and Esquerra, R.M., Water and Ligand Entry in Myoglobin: Assessing the Speed and Extent of Heme Pocket Hydration after CO Photodissociation, Proc. Natl. Acad. Sci., USA, 103, 1254-1259 (2006). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16432219

Ionascu, D., Gruis, F., Ye, X., Yu, A., Rosca, F., Beck, C., Demidov, A., Olson, J.S., and Champion, P.M., Temperature Dependent Studies of NO Recombination to Heme and Heme Proteins, J. Amer. Chem. Soc., 127, 16921-16934 (2005). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16316238

Olson, J. S. and Maillett, D. H Designing Recombinant Hemoglobin for Use as a Blood Substitute, Chapter 31 in Blood Substitutes (Robert Winslow, Kim D. Vandegriff, Eds.) Elsevier, London, UK (2005), pp. 354-374.

Dantsker, D., Roche, C., Samuni, U., Blouin, G., Olson, J.S., and Friedman, J., The Position 68(E11) Side Chain in Myoglobin Regulates Ligand Capture Bond Formation with the Heme Iron, and Internal Movement into the Xe Cavities, J. Biol. Chem., 280, 38740-38755 (2005). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16155005

Miranda, J.J.L., Maillett, D.H., Soman, J., and Olson, J.S., Thermoglobin, Oxygen-Avid Hemoglobin in a Eubacterial Hyperthermophile, J. Biol. Chem., 280, 36754-36761 (2005). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16135523

Nienhaus, K., Olson, J.S., Franzen, S., and Nienhaus, G.U., The Origin of Stark Splitting in the Initial Photoproduct State of MbCO, J. Amer. Chem. Soc., 127, 40-42 (2005). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15631438

Zhang, W., Olson, J.S., and Phillips, G.N., Jr.. Biophysical, Kinetic Characterization, and Crystallization of HemAT: An Aerotaxis Transducer from Bacillus subtilis, Biophys. J., 88, 2801-2814 (2005).  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15653746

Geuens, E., Dewilde, S., Hoogewijs, D., Pesce, A., Nienhaus, K., Olson, J.S., Vanfleteren, J., Bolognesi, M.. and Moens, L., Nerve Hemoglobins in Invertebrates, IUBMB Journal, 56, 653-664 (2004).  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15804828

Schotte, F., Soman, J., Olson, J.S., Wulff, M., and Anfinrud, P.A., Picosecond Time-Resolved X-ray Crystallography: Probing Protein Function in Real Time, J. Biol. Struct., 147, 235-246 (2004). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15450293

Pesce, A., Nardini, M., Ascenzi, P., Geuens, E., Dewilde, S., Moens, L., Bolognesi, M., Riggs, A.F., Hale, A., Deng, P., Nienhaus, G.U., Olson, J.S., and Nienhaus, K., ThrE11 Regulates O2 Affinity in Cerebratulus lacteus Minihemoglobin, J. Biol. Chem., 279, 33662-33672 (2004).  http://www.ncbi.nlmnih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15161908

Kundu, S., Blouin, G.C., Premer, S.A., Sarath, G., Olson, J.S., and Hargrove, M.S., TyrB10 Inhibits Stabilization of Bound CO and O2 in Soybean Leghemoglobin, Biochemistry, 43, 6241-6252 (2004). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15147208

Unno, M., Matsui, T., Chu, G.C., Couture, M., Yoshida, T., Rousseau, D.L., Olson, J.S., and Ikeda-Saito, M., Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae: Implications for Heme Oxygenase Function, J. Biol. Chem., 279, 21055-21061 (2004). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14966119

Puranik, M., Nielsen, S.B., Youn, H., Bourassa, J.L., Case, M.A., Hvitved, A.N., Tengroth, C., Balakrishnan, G., Thorsteinsson, M.V., Olson, J.S., Roberts, G.P., Groves, J.T., McLendon, G.L., and Spiro, T.G., Dynamics of Carbon Monoxide Binding to the CooA Protein, J. Biol. Chem., 279, 21096-21108 (2004). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14990568

Olson, J.S., Foley, E.W., Rogge, C., Tsai, A.-L., Doyle, M.P., and Lemon, D.D., NO Savenging and the Hypertensive Effect of Hb-based Blood Substitutes, Free Radical Biol. Med., 36, 685-697 (2004). http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14990349 

© Copyright Olson Lab June 2005 Department of Biochemistry and Cell Biology, Rice University
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