Daptomycin is a calcium dependent cyclic lipopeptide antibiotic
used against multidrug-resistant, gram-positive pathogens.
Daptomycin could insert into bacterial plasma membrane and
aggregate to form channels, which leads to slow leakage of ions
and loss of membrane potential. However, use of daptomycin
represents a risk for the development of resistance. According to
previous work in our lab, several |
